Long Covid as a multi-system disease: What the research tells us

This week’s blog is written by Dr Elisa Perego MA PhD (@elisaperego78), a patient and a researcher, who is affiliated as an Honorary Research Fellow to University College London and a Long Covid Kids champion.

Long Covid is a multi-system, heterogeneous disease. As a disease entity, Long Covid can basically affect all systems and organs in the body. This does not mean everyone with Long Covid will have proven pathology in every organ – but that damage, across different patient groups, can appear, basically, everywhere in the body. Some people will have physical damage documented only in one organ. Others will have physical impairment and biological abnormalities documented in many organs and body systems. Persistence of SARS-CoV-2 – or parts of it – in various body tissues is increasingly documented in the scientific literature.

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